Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
WB
Recomended Dilution
WB: 1:1000
Type Clonality
Polyclonal
Immunogen
Recombinant Protein of Fumarate hydratase, mitochondrial
Subcellular Location
[Isoform Cytoplasmic]: Cytoplasm, cytosol . Nucleus . Chromosome . Translocates to the nucleus in response to DNA damage: localizes to DNA double-strand breaks (DSBs) following phosphorylation by PRKDC. .
[Isoform Mitochondrial]: Mitochondrion .
[Isoform Mitochondrial]: Mitochondrion .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
2271
Observed Band
50kD
Other Name
Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)
Background
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in