Storage Conditions
-20°C/1 year
Applications
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:1000-2000, IHC 1:100-200
Type Clonality
Polyclonal
Immunogen
Synthetic Peptide of GABA A Receptor α2
Subcellular Location
Cell junction, synapse, postsynaptic cell membrane
Multi-pass membrane protein . Cell membrane
Multi-pass membrane protein . Cytoplasmic vesicle membrane . Cell projection, dendrite .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
282236
Observed Band
51kD
Other Name
Gamma-aminobutyric acid receptor subunit alpha-2 (GABA(A) receptor subunit alpha-2)
Background
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GA