Storage Conditions
-20°C/1 year
Applications
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
IHC 1:100-200
Type Clonality
Polyclonal
Immunogen
Synthetic Peptide of GABA B Receptor 2 AA range: 785-835
Subcellular Location
Cell membrane
Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane
Multi-pass membrane protein . Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane. In contrast, GABBR2 does not depend on GABBR1 for transport to the cell membrane. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
9568
Observed Band
106kD
Other Name
G-protein coupled receptor 51
GABA-B-R2
GABA-BR2
GABA-B receptor 2
GABABR2
GABBR2
GPR51
GPRC3B
Gamma-aminobutyric acid type B receptor subunit 2
Gb2
HG20
Background
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the re