Storage Conditions
-20°C/1 year
Applications
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:1000-2000, IHC 1:100-200
Type Clonality
Polyclonal
Immunogen
Synthetic Peptide of Ghrelin Receptor AA range: 290-370
Subcellular Location
Cell membrane
Multi-pass membrane protein.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
2693
Observed Band
41kD
Other Name
GH-releasing peptide receptor
GHRP
Ghrelin receptor)
Growth hormone secretagogue receptor type 1 (GHS-R
Background
This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserve
however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.[provided by RefSeq, Apr 2010],
this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin