Storage Conditions
-20°C/1 year
Applications
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthetic Peptide of Glutamate Receptor 1 AA range: 773-823
Subcellular Location
Cell membrane
Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane
Multi-pass membrane protein . Cell junction, synapse, postsynaptic density membrane
Multi-pass membrane protein . Cell junction, synapse, presynapse . Cell junction, synapse . Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression. Colocalizes with PDLIM4 in early endosomes. Displays a somatodendritic localization and
Multi-pass membrane protein . Cell projection, dendrite . Cell projection, dendritic spine . Early endosome membrane
Multi-pass membrane protein . Endoplasmic reticulum membrane
Multi-pass membrane protein . Recycling endosome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
2890
Observed Band
100kD
Other Name
AMPA-selective glutamate receptor 1
GluA1)
GluR-A
GluR-K1
Glutamate receptor 1 (GluR-1
Glutamate receptor ionotropic, AMPA 1
Background
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each posses