Storage Conditions
-20°C/1 year
Applications
WB
Recomended Dilution
WB: 1:2000
Type Clonality
Polyclonal
Immunogen
Synthetic Peptide of MeCP2 AA range: 313-363
Subcellular Location
Nucleus . Colocalized with methyl-CpG in the genome. Colocalized with TBL1X to the heterochromatin foci. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Human Gen
4204
Observed Band
53kD
Other Name
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Background
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG bi