Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
IF
IHC
WB
IHC
WB
Recomended Dilution
Western Blot: 1/500 - 1/2000.IHC-p:1:50-300. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the Internal region of human SOD-1.
Subcellular Location
Cytoplasm . Mitochondrion . Nucleus . Predominantly cytoplasmic
the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria. .
the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
6647
Observed Band
18kD
Other Name
SOD1
Superoxide dismutase 1
Superoxide dismutase [Cu-Zn]
hSod1
Superoxide dismutase 1
Superoxide dismutase [Cu-Zn]
hSod1
Background
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuri