Storage Conditions
-20°C/1 year
Applications
IF
IHC
Recomended Dilution
IHC: 1:200-500
Type Clonality
Polyclonal
Immunogen
Recombinant Protein of TLR1
Subcellular Location
Cell membrane
Single-pass type I membrane protein . Cytoplasmic vesicle, phagosome membrane
Single-pass type I membrane protein . Membrane raft . Golgi apparatus . Does not reside in lipid rafts before stimulation but accumulates increasingly in the raft upon the presence of the microbial ligand. In response to triacylated lipoproteins, TLR2:TLR
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
7096
Other Name
CD281
KIAA0012
TIL
TLR1
Toll-like receptor 1
Toll/interleukin-1 receptor-like protein
Background
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and func