Storage Conditions
-20°C/1 year
Applications
IF
IHC
Recomended Dilution
IHC: 1:200-500
Type Clonality
Polyclonal
Immunogen
Recombinant Protein of TLR4
Subcellular Location
Cell membrane
Single-pass type I membrane protein . Early endosome . Cell projection, ruffle . Upon complex formation with CD36 and TLR6, internalized through dynamin-dependent endocytosis (PubMed:20037584). Colocalizes with RFTN1 at cell membrane and then together wit
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
7099
Other Name
CD284
TLR4
Toll-like receptor 4
hToll
Background
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and func