Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human LC3A
Subcellular Location
Cytoplasmic vesicle, autophagosome membrane
Lipid-anchor . Cytoplasm, cytoskeleton . LC3-II binds to the autophagic membranes. .
Lipid-anchor . Endomembrane system
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
84557
Other Name
Autophagy-related ubiquitin-like modifier LC3 A
MAP1 light chain 3-like protein 1
MAP1A/MAP1B LC3 A
MAP1A/MAP1B light chain 3 A
Microtubule-associated protein 1 light chain 3 alpha)
Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A
Background
function:Probably involved in formation of autophagosomal vacuoles (autophagosomes).,PTM:The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipi