Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
IHC
WB
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human PCSK9
Subcellular Location
Cytoplasm. Secreted. Endosome. Lysosome. Cell surface. Endoplasmic reticulum. Golgi apparatus. Autocatalytic cleavage is required to transport it from the endoplasmic reticulum to the Golgi apparatus and for the secretion of the mature protein. Localizes
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
255738
Other Name
NARC-1
Neural apoptosis-regulated convertase 1
PC9
Proprotein convertase 9
Proprotein convertase subtilisin/kexin type 9 (EC 3.4.21.-
Subtilisin/kexin-like protease PC9)
Neural apoptosis-regulated convertase 1
PC9
Proprotein convertase 9
Proprotein convertase subtilisin/kexin type 9 (EC 3.4.21.-
Subtilisin/kexin-like protease PC9)
Background
cofactor:Calcium.,disease:Defects in PCSK9 are the cause of familial hypercholesterolemia 3 (FH3) [MIM:603776]. FH3 inheritance is autosomal dominant.,enzyme regulation:Inhibited by EGTA.,function:May be implicated in the differentiation of cortical neuro