Información del producto
Presenilin 2 rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
IHC
WB
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human Presenilin 2 AA range: 270-350
Subcellular Location
Endoplasmic reticulum membrane
Multi-pass membrane protein .
Multi-pass membrane protein . Golgi apparatus membrane
Multi-pass membrane protein .
Multi-pass membrane protein . Golgi apparatus membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
5664
Other Name
AD3LP
AD5
E5-1
EC 3.4.23.-
Presenilin-2 (PS-2
Presenilin-2 CTF subunit]
STM-2) [Cleaved into: Presenilin-2 NTF subunit
AD5
E5-1
EC 3.4.23.-
Presenilin-2 (PS-2
Presenilin-2 CTF subunit]
STM-2) [Cleaved into: Presenilin-2 NTF subunit
Background
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of