Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human LAT (Phospho Tyr255)
Subcellular Location
Cell membrane
Single-pass type III membrane protein . Present in lipid rafts.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
27040
Observed Band
38kD
Other Name
Linker for activation of T-cells family member 1 (36 kDa phospho-tyrosine adapter protein
p36-38)
pp36
Background
function:Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cel
which leads to the recruitment of multiple signaling molecules. Is one of the most prominently tyrosine-phosphorylated proteins detected following TCR engagement.,subcellular location:Present in lipid rafts.,subunit:When phosphorylated, interacts directly