Storage Conditions
-20°C/1 year
Applications
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human JAK3 (Phospho Tyr981)
Subcellular Location
Endomembrane system
Peripheral membrane protein . Cytoplasm .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
3718
Observed Band
73kD
Other Name
JAK-3
Janus kinase 3
L-JAK)
Leukocyte janus kinase
Tyrosine-protein kinase JAK3 (EC 2.7.10.2
Background
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,disease:Defects in JAK3 are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-negative (T(-)B(+)NK(-)SCID) [MIM