Información del producto
Met (Phospho Tyr1235) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human Met (Phospho Tyr1235)
Subcellular Location
Membrane
Single-pass type I membrane protein.
[Isoform 3]: Secreted.
Single-pass type I membrane protein.
[Isoform 3]: Secreted.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
4233
Observed Band
140170kD
Other Name
EC 2.7.10.1
HGF/SF receptor
Hepatocyte growth factor receptor (HGF receptor
Proto-oncogene c-Met
SF receptor
Scatter factor receptor
Tyrosine-protein kinase Met)
HGF/SF receptor
Hepatocyte growth factor receptor (HGF receptor
Proto-oncogene c-Met
SF receptor
Scatter factor receptor
Tyrosine-protein kinase Met)
Background
also known as papillary renal cell carcinoma 2 (RCCP2). HPRC is a form of inherited kidney cancer characterized by a predisposition to develop multiple, bilateral papillary renal tumors. The pattern of inheritance is consistent with autosomal dominant tra
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,disease:Activation of MET after rearrangement with the TPR gene produces an oncogenic protein.,disease:Defects in MET are a cause of hepatocellular carcinoma (HCC) [
prevents interaction with GRB2 and suppresses hepatocyte growth factor-induced cell proliferation.,
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,disease:Activation of MET after rearrangement with the TPR gene produces an oncogenic protein.,disease:Defects in MET are a cause of hepatocellular carcinoma (HCC) [
prevents interaction with GRB2 and suppresses hepatocyte growth factor-induced cell proliferation.,