Storage Conditions
-20°C/1 year
Applications
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human Sp3 (Acetyl Lys551)
Subcellular Location
Nucleus. Nucleus, PML body. Localizes to the nuclear periphery and in nuclear dots when sumoylated. Some localization in PML nuclear bodies.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
6670
Observed Band
85kD
Other Name
Transcription factor Sp3 (SPR-2)
Background
This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several