Storage Conditions
-20°C/1 year
Applications
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human Smad2/3 (Acetyl Lys420/378)
Subcellular Location
Cytoplasm . Nucleus . Cytoplasmic and nuclear in the absence of TGF-beta. On TGF-beta stimulation, migrates to the nucleus when complexed with SMAD4 (PubMed:9865696, PubMed:21145499). On dephosphorylation by phosphatase PPM1A, released from the SMAD2/SMAD
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
4087
Observed Band
55kD
Other Name
JV18-1
Mad-related protein 2
Mothers against DPP homolog 2
Mothers against decapentaplegic homolog 2 (MAD homolog 2
SMAD 2
SMAD family member 2
Smad2
hMAD-2
hSMAD2)