Storage Conditions
-20°C/1 year
Applications
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human MMP8 (Cleaved-Leu101)
Subcellular Location
Cytoplasmic granule. Secreted, extracellular space, extracellular matrix . Stored in intracellular granules.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
4317
Observed Band
40 53kD
Other Name
MMP-8
Matrix metalloproteinase-8
Neutrophil collagenase (EC 3.4.24.34
PMNL-CL)
PMNL collagenase
Background
catalytic activity:Cleavage of interstitial collagens in the triple helical domain. Unlike EC 3.4.24.7, this enzyme cleaves type III collagen more slowly than type I.,cofactor:Binds 2 zinc ions per subunit.,cofactor:Binds 3 calcium ions per subunit.,domai