Información del producto
MMP1 (Cleaved-Ile271) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human MMP1 (Cleaved-Ile271)
Subcellular Location
Secreted, extracellular space, extracellular matrix .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
4312
Observed Band
22 53kD
Other Name
27 kDa interstitial collagenase]
Fibroblast collagenase
Interstitial collagenase (EC 3.4.24.7
MMP-1) [Cleaved into: 22 kDa interstitial collagenase
Matrix metalloproteinase-1
Fibroblast collagenase
Interstitial collagenase (EC 3.4.24.7
MMP-1) [Cleaved into: 22 kDa interstitial collagenase
Matrix metalloproteinase-1
Background
catalytic activity:Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at 775-Gly-|-Ile-776 in the alpha-1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' i
the catalytic N-terminal, and the C-terminal which is involved in substrate specificity and in binding TIMP (tissue inhibitor of metalloproteinases).,enzyme regulation:Can be activated without removal of the activation peptide.,function:Cleaves collagens
the catalytic N-terminal, and the C-terminal which is involved in substrate specificity and in binding TIMP (tissue inhibitor of metalloproteinases).,enzyme regulation:Can be activated without removal of the activation peptide.,function:Cleaves collagens