Información del producto
ITGA5 (heavy chain, Cleaved-Arg894) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human ITGA5 (heavy chain, Cleaved-Arg894)
Subcellular Location
Membrane
Single-pass type I membrane protein. Cell junction, focal adhesion . Cell surface .
Single-pass type I membrane protein. Cell junction, focal adhesion . Cell surface .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
3678
Observed Band
94 110kD
Other Name
CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain
Fibronectin receptor subunit alpha
Integrin alpha-5 (CD49 antigen-like family member E
Integrin alpha-5 light chain]
Integrin alpha-F
VLA-5
Fibronectin receptor subunit alpha
Integrin alpha-5 (CD49 antigen-like family member E
Integrin alpha-5 light chain]
Integrin alpha-F
VLA-5
Background
function:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarc