Información del producto
Adrenocorticotropin(ACTH) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
IF
IHC
WB
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-200, WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human Adrenocorticotropin(ACTH)
Subcellular Location
Secreted . Melanocyte-stimulating hormone alpha and beta-endorphin are stored in separate granules in hypothalamic POMC neurons, suggesting that secretion may be under the control of different regulatory mechanisms. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
5443
Observed Band
57kD
Other Name
ACTH)
Beta-endorphin
Corticotropin (Adrenocorticotropic hormone
Corticotropin-like intermediary peptide (CLIP)
Corticotropin-lipotropin) [Cleaved into: NPP
Lipotropin beta (Beta-LPH)
Lipotropin gamma (Gamma-LPH)
Melanotropin alpha (Alpha-MSH)
Melanotropin beta (Beta-MSH)
Melanotropin gamma (Gamma-MSH)
Met-enkephalin]
Potential peptide
Pro-opiomelanocortin (POMC
Beta-endorphin
Corticotropin (Adrenocorticotropic hormone
Corticotropin-like intermediary peptide (CLIP)
Corticotropin-lipotropin) [Cleaved into: NPP
Lipotropin beta (Beta-LPH)
Lipotropin gamma (Gamma-LPH)
Melanotropin alpha (Alpha-MSH)
Melanotropin beta (Beta-MSH)
Melanotropin gamma (Gamma-MSH)
Met-enkephalin]
Potential peptide
Pro-opiomelanocortin (POMC
Background
This gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depe
adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used
adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used