Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:1000-2000
Type Clonality
Polyclonal
Immunogen
Synthesized phosho peptide around human ALK (Tyr1078)
Subcellular Location
Cell membrane
Single-pass type I membrane protein . Membrane attachment is essential for promotion of neuron-like differentiation and cell proliferation arrest through specific activation of the MAP kinase pathway. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
238
Observed Band
150-240kD
Other Name
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Background
This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain