Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1：500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human ATF6A AA range: 221-271
Subcellular Location
Endoplasmic reticulum membrane
Single-pass type II membrane protein . Golgi apparatus membrane
Single-pass type II membrane protein . Translocates from the endoplasmic reticulum to the Golgi, where it is processed. .
[Processed cyclic AMP-dependent transcription factor ATF-6 alpha]: Nucleus . Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus (PubMed:10564271, PubMed:12782636). THBS4 promotes its nuclear shuttling (By similarity).
Single-pass type II membrane protein . Golgi apparatus membrane
Single-pass type II membrane protein . Translocates from the endoplasmic reticulum to the Golgi, where it is processed. .
[Processed cyclic AMP-dependent transcription factor ATF-6 alpha]: Nucleus . Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus (PubMed:10564271, PubMed:12782636). THBS4 promotes its nuclear shuttling (By similarity).
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
22926
Observed Band
90kD
Background
This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembr