Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000, ELISA(peptide)1:5000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human Caspase 10 (p23/17, Cleaved-Val220)
Subcellular Location
cytosol,CD95 death-inducing signaling complex,ripoptosome,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
843
Observed Band
58+23kD
Other Name
Apoptotic protease Mch-4
Caspase-10 (CASP-10
Caspase-10 subunit p12]
EC 3.4.22.63
FAS-associated death domain protein interleukin-1B-converting enzyme 2
FLICE2
ICE-like apoptotic protease 4) [Cleaved into: Caspase-10 subunit p23/17
Background
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo pro