Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human CLCN3 AA range: 597-647
Subcellular Location
Multi-pass membrane protein . Cell membrane
Multi-pass membrane protein . Cell projection, ruffle membrane
Multi-pass membrane protein . Isoform 1 is localized mainly in late endosomes. .
Multi-pass membrane protein . Isoform 2 is mainly enriched in the Golgi (PubMed:12471024). Colocalizes with SLC9A3R1/EBP50 in membrane ruffles (PubMed:11967229). .
Multi-pass membrane protein . Late endosome membrane
Multi-pass membrane protein . Lysosome membrane
[Isoform 1]: Early endosome membrane
[Isoform 2]: Golgi apparatus membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
1182
Background
This gene encodes a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domai