Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1：500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human CTNS AA range: 234-284
Subcellular Location
Multi-pass membrane protein .
Multi-pass membrane protein . AP-3 complex is required for localization to the lysosome. .
Multi-pass membrane protein . Cell membrane
Multi-pass membrane protein . Melanosome membrane
[Isoform 1]: Lysosome membrane
[Isoform 2]: Lysosome membrane
Multi-pass membrane protein . AP-3 complex is required for localization to the lysosome. .
Multi-pass membrane protein . Cell membrane
Multi-pass membrane protein . Melanosome membrane
[Isoform 1]: Lysosome membrane
[Isoform 2]: Lysosome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
1497
Background
This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage