DAZ4 rabbit pAb
  • DAZ4 rabbit pAb
ELK

DAZ4 rabbit pAb

Ref: ELK-ES17017-100μL
100μL

Información del producto

Información adicional
Storage Conditions -20°C/1 year
Applications WB
Concentration 1 mg/ml
Recomended Dilution WB 1:500-2000
Type Clonality Polyclonal
Immunogen Synthesized peptide derived from human DAZ4 AA range: 525-575
Subcellular Location Cytoplasm . Nucleus . Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates t
Iso type IgG
Tissue Source Rabbit
Reactivity Human
Mouse
Rat
Human Gen 57135
Background This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important
one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat
the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified
this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains two copies of the 10.8 kb repeat. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 201