Storage Conditions
-20°C/1 year
Applications
IP
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 IP 1:200
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human DHSO
Subcellular Location
Mitochondrion membrane
Peripheral membrane protein . Cell projection, cilium, flagellum . Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium an
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
6652
Background
EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1
MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway)
Sorbitol dehydrogenase (SORD