Storage Conditions
-20°C/1 year
Applications
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-200
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human FLNC AA range: 335-385
Subcellular Location
Cytoplasm . Membrane
Peripheral membrane protein . Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, Z line . A small amount localizes at membranes. In striated muscle cells, it predominantly localizes in myofibrillar Z lines, while a minor fraction localizes with su
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
2318
Background
This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskele