Información del producto
GRK2 (Phospho-Tyr86) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
IF
IHC
WB
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-200, WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human GRK2 (Phospho-Tyr86)
Subcellular Location
Cytoplasm . Cell membrane . Cell junction, synapse, postsynapse . Cell junction, synapse, presynapse .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
156
Observed Band
75kD
Other Name
Beta-adrenergic receptor kinase 1 (Beta-ARK-1
EC 2.7.11.15
G-protein coupled receptor kinase 2)
EC 2.7.11.15
G-protein coupled receptor kinase 2)
Background
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the act