Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human HERC3 AA range: 985-1035
Subcellular Location
Cytoplasm. Cytoplasmic vesicle. Also found in vesicular-like structures.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
8916
Background
This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced tra