Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human HSH2D AA range: 288-338
Subcellular Location
Cytoplasm. Nucleus.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
84941
Observed Band
38kD
Other Name
Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X)
Background
MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 2003 [PubMed 12960172]).[supplied by OMIM, Mar 2008],
T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR