Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000, ELISA(peptide)1:5000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized pospho peptide derived from human HSP27 (Phospho S78/82)
Subcellular Location
Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, spindle . Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuc
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
3315
Observed Band
27kD
Other Name
28 kDa heat shock protein
Estrogen-regulated 24 kDa protein
HSP 27
Heat shock 27 kDa protein
Heat shock protein beta-1 (HspB1
SRP27)
Stress-responsive protein 27
Background
The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in