Información del producto
IGF2R (Phospho-Ser2484) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
IF
IHC
WB
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-200, WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human IGF2R (Phospho-Ser2484)
Subcellular Location
Golgi apparatus membrane
Single-pass type I membrane protein . Endosome membrane
Single-pass type I membrane protein . Mainly localized in the Golgi at steady state and not detectable in lysosome (PubMed:18817523). Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface (PubMed:10900005). .
Single-pass type I membrane protein . Endosome membrane
Single-pass type I membrane protein . Mainly localized in the Golgi at steady state and not detectable in lysosome (PubMed:18817523). Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface (PubMed:10900005). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
3482
Observed Band
300kD
Other Name
300 kDa mannose 6-phosphate receptor
CD antigen CD222)
CI-MPR
Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor
IGF-II receptor
Insulin-like growth factor 2 receptor
Insulin-like growth factor II receptor
M6P/IGF2 receptor
M6P/IGF2R
M6PR
MPR 300
CD antigen CD222)
CI-MPR
Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor
IGF-II receptor
Insulin-like growth factor 2 receptor
Insulin-like growth factor II receptor
M6P/IGF2 receptor
M6P/IGF2R
M6PR
MPR 300
Background
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking
however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015],
however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015],