Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human INT4 AA range: 10-60
Subcellular Location
Nucleus .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
92105
Observed Band
105kD
Other Name
Integrator complex subunit 4 (Int4)
Background
INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A
MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1
MIM 180680) and U2 (RNU2
MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008],