Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human INT7 AA range: 364-414
Subcellular Location
Nucleus . Chromosome . Cytoplasm . Localizes to sites of DNA damage in a H2AX-independent manner.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
25896
Observed Band
105kD
Other Name
Integrator complex subunit 7 (Int7)
Background
This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding