Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human MBD2 AA range: 110-160
Subcellular Location
Nucleus . Nuclear, in discrete foci. Detected at replication foci in late S phase.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
8932
Background
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG bi