Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human NPC1 AA range: 1073-1123
Subcellular Location
Late endosome membrane
Multi-pass membrane protein .
Multi-pass membrane protein . Lysosome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
4864
Background
This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13