Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human NPC2 AA range: 9-59
Subcellular Location
Secreted . Endoplasmic reticulum . Lysosome . Interaction with cell-surface M6PR mediates endocytosis and targeting to lysosomes. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
10577
Background
This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disea