Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human NRAM2 AA range: 474-524
Subcellular Location
Endosome membrane
Multi-pass membrane protein . Also found in extracellular vesicles different from exosomes. .
Multi-pass membrane protein. Cell membrane
Multi-pass membrane protein . Early endosome .
Multi-pass membrane protein . Mitochondrion outer membrane
[Isoform 2]: Cell membrane
Multi-pass membrane protein . Also found in extracellular vesicles different from exosomes. .
Multi-pass membrane protein. Cell membrane
Multi-pass membrane protein . Early endosome .
Multi-pass membrane protein . Mitochondrion outer membrane
[Isoform 2]: Cell membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
4891
Observed Band
60kD
Other Name
Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent cation transporter 1) (Divalent metal transporter 1) (DMT-1)
Background
This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload.