Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human PDLI2 AA range: 190-240
Subcellular Location
Cytoplasm . Nucleus . May be partially nuclear.
[Isoform 1]: Cytoplasm, cytoskeleton. Colocalizes with beta-1 integrin (ITGB1) and alpha-actinin but not with paxillin (PXN).
[Isoform 2]: Cytoplasm, cytoskeleton.
[Isoform 3]: Nucleus.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
64236
Observed Band
38kD
Other Name
PDZ and LIM domain protein 2 (PDZ-LIM protein mystique)
Background
This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded