Storage Conditions
-20°C/1 year
Applications
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized phosho peptide around human PKCα (Thr638 and 641)
Subcellular Location
Cytoplasm . Cell membrane
Peripheral membrane protein . Mitochondrion membrane
Peripheral membrane protein . Nucleus .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
5578
Observed Band
76kD
Other Name
Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)
Background
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved