Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
IF
IHC
WB
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-200, WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human PKM2 AA range: 301-350
Subcellular Location
[Isoform M1]: Cytoplasm .
[Isoform M2]: Cytoplasm . Nucleus . Translocates to the nucleus in response to various signals, such as EGF receptor activation or apoptotic stimuli (PubMed:17308100, PubMed:22056988, PubMed:24120661). Nuclear translocation is promoted by acetylation by E
[Isoform M2]: Cytoplasm . Nucleus . Translocates to the nucleus in response to various signals, such as EGF receptor activation or apoptotic stimuli (PubMed:17308100, PubMed:22056988, PubMed:24120661). Nuclear translocation is promoted by acetylation by E
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
5315
Observed Band
58kD
Other Name
CTHBP
Cytosolic thyroid hormone-binding protein
OIP-3
Opa-interacting protein 3
Pyruvate kinase 2/3
Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40
Pyruvate kinase muscle isozyme
THBP1
Thyroid hormone-binding protein 1
Tumor M2-PK
p58)
Cytosolic thyroid hormone-binding protein
OIP-3
Opa-interacting protein 3
Pyruvate kinase 2/3
Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40
Pyruvate kinase muscle isozyme
THBP1
Thyroid hormone-binding protein 1
Tumor M2-PK
p58)
Background
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyro