Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
IHC
WB
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human PSB11 AA range: 62-112
Subcellular Location
Cytoplasm . Nucleus .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
122706
Background
MIM 147570) and are preferentially incorporated into proteasomes to make immunoproteasomes. PSMB11, or beta-5t, is a catalytic subunit expressed exclusively in cortical thymic epithelial cells (Murata et al., 2007 [PubMed 17540904]).[supplied by OMIM, Mar
MIM 176847), and beta-5i (PSMB8
MIM 177045), beta-2i (PSMB10
MIM 177046), are induced by gamma-interferon (IFNG
MIM 600306). Three additional subunits, beta-1i (PSMB9
MIM 600307), beta-2 (PSMB7
MIM 604030), and beta-5 (PSMB5
Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes, complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric
MIM 176847), and beta-5i (PSMB8
MIM 177045), beta-2i (PSMB10
MIM 177046), are induced by gamma-interferon (IFNG
MIM 600306). Three additional subunits, beta-1i (PSMB9
MIM 600307), beta-2 (PSMB7
MIM 604030), and beta-5 (PSMB5
Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes, complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric