Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized phosho peptide around human Rad17 (Ser635)
Subcellular Location
Nucleus . Phosphorylated form redistributes to discrete nuclear foci upon DNA damage.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
5884
Observed Band
77kD
Other Name
Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog)
Background
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity w