Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human SC5AC AA range: 84-134
Subcellular Location
Apical cell membrane
Multi-pass membrane protein . Detected at the brush border membrane of the kidney. Colocalizes with viementin in Mueller cells (By similarity). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
159963
Background
Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the h