Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human SGPP1 AA range: 47-97
Subcellular Location
Endoplasmic reticulum membrane
Multi-pass membrane protein .
Multi-pass membrane protein . Cell membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
81537
Background
Le Stunff et al., 2007 [PubMed 17895250]).[supplied by OMIM, Jun 2009],
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 1085935