Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized phosho peptide around human SMC1 (Ser360)
Subcellular Location
Nucleus . Chromosome . Chromosome, centromere, kinetochore . Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
8243
Observed Band
143kD
Other Name
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8)
Background
structural maintenance of chromosomes 1A(SMC1A) Homo sapiens Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohes