Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human SPTC3 AA range: 341-391
Subcellular Location
Endoplasmic reticulum membrane
Single-pass membrane protein .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
55304
Background
EC 2.3.1.50), which catalyzes the rate-limiting step of the de novo synthesis of sphingolipids (Hornemann et al., 2006 [PubMed 17023427]). SPT contains 2 main subunits: the common SPTLC1 subunit (MIM 605712) and either SPTLC2 (MIM 605713) or its isoform S
The SPTLC3 gene encodes an isoform of the third subunit of serine palmitoyltransferase (SPT