SREBP-1 (Acetyl-Lys324) rabbit pAb
  • SREBP-1 (Acetyl-Lys324) rabbit pAb
ELK

SREBP-1 (Acetyl-Lys324) rabbit pAb

Ref: ELK-ES12957-100μL
100μL

Información del producto

SREBP-1 (Acetyl-Lys324) rabbit pAb

Click here for product file

Click here for product image

Click here for second product image

Información adicional
Storage Conditions -20°C/1 year
Applications IF
IHC
WB
Concentration 1 mg/ml
Recomended Dilution IHC-p 1:50-200, WB 1:500-2000
Type Clonality Polyclonal
Immunogen Synthesized peptide derived from human SREBP-1 (Acetyl-Lys324)
Subcellular Location Multi-pass membrane protein . At high sterol concentrations, the SCAP-SREBP is retained in the endoplasmic reticulum. Low sterol concentrations promote recruitment into COPII-coated vesicles and transport of the SCAP-SREBP to the Golgi, where it is proces
Multi-pass membrane protein . Cytoplasmic vesicle, COPII-coated vesicle membrane
Multi-pass membrane protein . Golgi apparatus membrane
[Isoform SREBP-1aDelta]: Nucleus .
[Isoform SREBP-1cDelta]: Nucleus .
[Processed sterol regulatory element-binding protein 1]: Nucleus .
[Sterol regulatory element-binding protein 1]: Endoplasmic reticulum membrane
Iso type IgG
Tissue Source Rabbit
Reactivity Human
Mouse
Rat
Human Gen 6720
Observed Band 130kD
Other Name Class D basic helix-loop-helix protein 1
Sterol regulatory element-binding protein 1 (SREBP-1
Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1]
bHLHd1
Background This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor